L-HPC (Low-substituted Hydroxypropyl Cellulose) is mainly used as a tablet-disintegration accelerator. It should be applied to tablets that show poor disintegration properties.
By accelerating the disintegration and increasing the fineness of a dispersion, it improves the bioavailability of the API. For drugs that can't be easily moulded, L-HPC can increase the hardness of the tablet. It is suitable for use in both wet and dry granulation. It can also be added as an adhesive in starch paste.
|Loss on drying (%)||≤5.0|
|Residue on ignition (WT%)||≤1.0|
|Heavy metals (ppm)||≤20|
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